Table 3.
Effect size (d or r) | |||||
---|---|---|---|---|---|
Behavioral measure | Main effect of injury | p value | Power | Mild | Severe |
OF distance traveled, Day 1 | Severe > Sham | 0.0034 | 0.8753 | N/A | 0.7322 |
OF distance traveled, Day 10 | Severe > Sham | <0.0001 | 1.000 | N/A | 1.588 |
OF distance traveled, Day 20 | Severe > Sham | <0.0001 | 1.000 | N/A | 1.523 |
OF center activity, Day 1 | Sham > Severe | .0012 | 0.9291 | N/A | 0.8633 |
OF center activity, Day 10 | Sham > Severe | 0.0003 | 0.9664 | N/A | 0.9834 |
OF center activity, Day 20 | Sham > Severe | <0.0001 | 0.9947 | N/A | 1.036 |
LDB time in dark, Day 2 | Sham > Severe | 0.0004 | 0.9644 | N/A | 0.9591 |
EZM distance traveled, Day 21, Male | Severe > Sham | <0.001 | – | N/A | 0.4074 |
EZM distance traveled, Day 21, Female | Severe > Sham | <0.001 | – | N/A | 0.4349 |
EZM time in dark quadrants | Sham > Severe | 0.0097 | 0.7908 | N/A | 0.6401 |
EZM head dips, Day 2 | Sham > Severe | 0.0027 | 0.8889 | N/A | 0.7764 |
EZM head dips, Day 21 | Severe, Mild > Sham | <0.0001 | 0.9868 | 1.014 | 0.9473 |
EZM U turns, Day 2 | Sham > Mild, Severe | 0.0045 | 0.8557 | 0.7802 | 0.7319 |
MBT marbles buried, Male | Sham > Severe | <0.0001 | 0.9964 | N/A | 1.054 |
MBT marbles buried, Female | Sham > Mild, Severe | 0.0002 | 0.9832 | 1.027 | 1.448 |
Shown are the behavioral measures in the current experiment for which a significant difference between injured mice and sham controls was found. P values from analyses of variance (ANOVAs), power (1 – β) and calculated effect sizes (Cohen's d) are provided, and Cohen's d = . Effect size r for distance traveled in the EZM on day 21 was calculated as .
OF, open field; EZM, elevated zero maze; MBT, marble burying test.