Table 3.
The accumulated excretion ratio of ponatinib in urine and feces at designated times (12, 24, 48, 72, 96, 120, 144 h) after i.g. administration of 15.0 mg/kg,
| Time (h) | Accumulated excretion ratio (%) | |
|---|---|---|
| Urine | Feces | |
| 12 | 0.07 ± 0.04 | 3.70 ± 2.67 |
| 24 | 0.14 ± 0.06 | 20.90 ± 9.56 |
| 48 | 0.21 ± 0.08 | 23.80 ± 8.66 |
| 72 | 0.22 ± 0.09 | 25.28 ± 7.96 |
| 96 | 0.23 ± 0.10 | 25.72 ± 7.79 |
| 120 | 0.24 ± 0.10 | 26.16 ± 7.70 |
| 144 | 0.24 ± 0.10 | 26.17 ± 7.70 |