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Recommended investigations/staging policy for SCC of the anus
| T1N0T1N0 | T1N+T1N1 | T2N0T2 N0 | T2N+T2N1 | T3N0T3N0 | T3N+T3N1 | T4T4 | |
|---|---|---|---|---|---|---|---|
| FBC, E+U, LFTs | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
|
SCCAg NR (1–150 ng/dl) |
Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| CT scan of whole body | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Ultrasound | Sometimes | Sometimes | No | No | No | No | No |
| MRI | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Diffusion-weighted MRI | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| PET/CT |
No Unless SCCAg > 150 |
Yes | Yes | Yes | Yes | Yes | Yes |
