Table 6.
Summary of Unadjusted and Adjusted Association Between Physical Function (SF-12) and Demographic variables, CRIC, United States, 2003–2008
| Univariable | Multivariable | ||||||
|---|---|---|---|---|---|---|---|
| Clinical characteristic | β | SE | P-value | β | SE | P-value | |
| Intercept | 58.59 | 1.58 | <0.001 | ||||
| HTN | −4.42 | 0.55 | <0.001 | ||||
| Hypercholesterolemia | −2.93 | 0.50 | <0.001 | ||||
| Smoking (overall) |
<0.001 | <0.001 | |||||
| Former | −2.06 | 0.42 | <0.001 | −1.32 | 0.38 | 0.001 | |
| Current | −3.65 | 0.62 | <0.001 | −3.38 | 0.56 | <0.001 | |
| Diabetes | −5.01 | 0.38 | <0.001 | −1.86 | 0.37 | <0.001 | |
| Age | −0.14 | 0.02 | <0.001 | −0.07 | 0.02 | <0.001 | |
| CHF | −8.42 | 0.69 | <0.001 | −4.20 | 0.66 | <0.001 | |
| CAD | −5.82 | 0.49 | <0.001 | −3.35 | 0.48 | <0.001 | |
| Race (overall) |
<0.001 | <0.001 | |||||
| Black | −3.92 | 0.41 | <0.001 | −1.49 | 0.38 | <0.001 | |
| Other | −2.40 | 0.63 | <0.001 | −1.62 | 0.62 | 0.009 | |
| BMI | −0.44 | 0.02 | <0.001 | −0.32 | 0.02 | <0.001 | |
| eGFR | 0.18 | 0.01 | <0.001 | 0.08 | 0.01 | <0.001 | |
| Sex (Women) |
−4.15 | 0.39 | <0.001 | −4.00 | 0.40 | <0.001 | |
| ABI (overall) |
<0.001 | 0.002 | |||||
| ABI<0.6 | −5.80 | 1.29 | <0.001 | −6.03 | 1.66 | <0.001 | |
| ABI≥0.6<0.9 | −5.17 | 0.61 | <0.001 | −1.05 | 0.79 | 0.184 | |
| ABI ≥1.3 | −0.44 | 0.84 | 0.603 | 0.10 | 0.94 | 0.916 | |
| Sex(Women)*ABI overall | <0.001 | ||||||
| Sex*ABI<0.6 | 8.82 | 2.29 | <0.001 | ||||
| Sex*ABI≥0.6<0.9 | −1.03 | 1.09 | 0.345 | ||||
| Sex*ABI≥1.3 | 1.37 | 1.57 | 0.381 | ||||
| Clinical center (overall) |
<0.001 | <0.001 | |||||
*
ABI-Ankle Brachial Index; BMI-Body Mass Index; CAD-coronary artery disease; CHF-congestive heart failure; eGFR-estimated glomerular filtration rate; SE-standard error
†
Covariates were added using forward selection method
‡
0.9≥ABI <1.3 used as the referent category