Table 2.

Clinicopathologic correlation of ZEB-1 and E-cadherin expression in OSCC

Variables	Total no	ZEB-1 expression		P-value	E-cadherin expression		P-value
		Positive	Negative		Positive	Loss
Gender				0.380			0.200
Male	75	34	41		37	38
Female	45	30	15		16	29
Age (years)				0.398			0.618
≤60	54	26	28		22	32
>60	66	38	28		31	35
Smoker				0.554			0.521
No	49	26	23		22	27
Yes	71	38	33		31	40
Alcohol				0.199			0.271
No	67	39	27		26	40
Yes	53	25	29		27	27
Tumor site				0.715			0.806
Tongue	52	28	24		26	26
Oral floor	26	16	10		11	15
Gingiva	20	11	9		8	12
Cheek	15	6	9		5	10
Hard palate	7	3	4		3	4
T stage				0.362			0.538
T1 + T2	73	36	37		32	41
T3 + T4	47	28	19		21	26
Differentiation				0.000			0.004
Well	39	10	29		25	14
Moderate/poor	81	54	27		28	53
Lymph node metastasis				0.000			0.003
No	62	20	42		36	26
Yes	58	44	14		17	41
Recurrence				0.008			0.531
No	65	27	38		29	36
Yes	55	37	18		24	31

Abbreviations: ZEB-1, zinc-finger E-box binding homeobox 1; OSCC, oral cavity squamous cell carcinoma.