Table 3.
Univariate and multivariate analysis of factors affecting overall survival
| Variables | Univariate
|
Multivariate
|
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Differentiation | 0.334 | 0.147–0.640 | 0.001 | 0.606 | 0.289–1.271 | 0.185 |
| Lymph node metastasis | 0.429 | 0.252–0.717 | 0.001 | 0.655 | 0.337–1.271 | 0.211 |
| ZEB-1 expression | 0.278 | 0.164–0.501 | 0.000 | 0.502 | 0.255–0.988 | 0.046 |
| E-cadherin loss | 2.025 | 1.171–3.499 | 0.012 | 1.256 | 0.672–2.348 | 0.475 |
| Recurrence | 0.481 | 0.291–0.796 | 0.004 | 0.482 | 0.275–0.847 | 0.011 |
Abbreviations: ZEB-1, zinc-finger E-box binding homeobox 1; CI, confidence interval; HR, hazard ratio.