Table 1. Frequency of DLA-DRB1/-DQA1/-DQB1 haplotypes in collies and Shetland sheepdogs.
| COLLIE | |||||
| DLA-DRB1*/-DQA1*/-DQB1* | Cases (2n = 80) | Controls (2n = 370) | OR | 95% CI | P-value |
| 002:01/009:01/001:01 | 74 | 353 | 0.59 | 0.23–1.56 | 0.40 |
| 006:01/050:11/007:01 | 0 | 3 | - | - | - |
| 015:01/009:01/001:01 | 6 | 14 | 2.06 | 0.77–5.54 | 0.23 |
| SHETLAND SHEEPDOG | |||||
| DLA-DRB1*/-DQA1*/-DQB1* | Cases (2n = 184) | Controls (2n = 410) | OR | 95% CI | P-value |
| 002:01/009:01/001:01 † | 158 | 301 | 2.20 | 1.38–3.52 | 0.0010 |
| 015:01/009:01/001:01 | 1 | 6 | 0.37 | 0.04–3.08 | 0.4454 |
| 023:01/003:01/005:01 | 24 | 102 | 0.45 | 0.28–0.73 | 0.0011 |
| Other haplotypes | 1 | 1 | - | - | - |
The number of times each haplotype was observed is reported for cases and controls with odds ratios (OR), 95% confidence intervals, and Fisher’s exact two-tailed P-values. Significant statistics are bolded.
†71 out of 92 cases and 109 out of 205 controls were homozygous for the 002:01/009:01/001:01 haplotype (OR = 2.98, 95% CI = 1.70–5.21, P-val = 0.0001).