Skip to main content
. 2016 Dec 21;25(3):332–340. doi: 10.1038/ejhg.2016.169

Figure 3.

Figure 3

European and Amerindian A1 HTT haplotype frequencies across all reference populations of the 1000 Genomes Project. Latin American reference populations have the highest frequency of the Amerindian A1 variant haplotype, constituting the majority of all A1 haplotypes among Colombians (CLM), Mexicans (MXL), and Peruvians (PEL). Amerindian A1 also constitutes a third of all A1 haplotypes among Puerto Ricans (PUR). In contrast, Amerindian A1 is rare in European and South Asian populations where the parent A1 haplotype is common: British (GBR), Finnish (FIN), Iberian (IBS), Toscani Italian (TSI), Utah Caucasian (CEU), Bengali (BEB), Gujarati (GIH), Telugu (ITU), Punjabi (PJL), and Sri Lankan Tamil (STU). The parent A1 haplotype is entirely absent in Black African and East Asian populations, except for one instance in a Gambian individual. European and Amerindian A1 are both found among admixed Africans from the United States (ASW) and Barbados (ACB).