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. 2016 Oct 4;6(10):e910. doi: 10.1038/tp.2016.181

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Copyright © 2016 The Author(s)

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Inhibitory axon innervations on the glutamatergic neurons are downregulated in the medial prefrontal cortex (mPFC) from the depression-like mice. (a) The innervations of GABAergic axons (green) on the apical dendrites of glutamatergic neuron (yellow) in the mPFC from a control mouse. (b) The innervations of GABAergic axons (green) on the apical dendrites of glutamatergic neuron (yellow) in the mPFC from a depression-like mouse. (c) The comparisons of innervations per 100 μm dendrite from depression-like mice (red bar, n=80 apical dendrites from seven mice) and controls (blue, n=78 apical dendrites from six mice; ***P<0.001).