Table 2.
Protocol 1 | Protocol 2 | Protocol 3 | ||||
---|---|---|---|---|---|---|
Control | SDF | Control | L-NMMA | Control | SDF+L-NMMA | |
Heart Rate (beat/min) | ||||||
Baseline | 60 ± 4 | 65 ± 4† | 61 ± 2 | 61 ± 2 | 62 ± 2 | 58 ± 3 |
5 minutes | 64 ± 3* | 70 ± 5*† | 64 ± 2* | 63 ± 2* | 65 ± 2* | 63 ± 3* |
Δ | 4 ± 1 | 5 ± 1 | 3 ± 2 | 2 ± 1 | 3 ± 1 | 4 ± 1 |
Mean Arterial Blood Pressure (mmHg) | ||||||
Baseline | 91 ± 3 | 91 ± 3 | 88 ± 2 | 90 ± 1† | 92 ± 3 | 91 ± 3 |
5 minutes | 94 ± 2 | 93 ± 3 | 90 ± 2* | 92 ± 2*† | 91 ± 3 | 94 ± 4 |
Δ | 3 ± 2 | 2 ± 1 | 2 ± 1 | 2 ± 1 | −1 ± 1 | 3 ± 1 |
Brachial Artery Diameter (cm) | ||||||
Baseline | 0.36 ± 0.02 | 0.36 ± 0.02 | 0.38 ± 0.01 | 0.38 ± 0.01 | 0.32 ± 0.01 | 0.32 ± 0.02 |
5 minutes | 0.38 ± 0.02* | 0.38 ± 0.02* | 0.40 ± 0.01* | 0.40 ± 0.01* | 0.34 ± 0.01* | 0.33 ± 0.02* |
Δ | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.00 | 0.02 ± 0.00 | 0.02 ± 0.00 | 0.01 ± 0.01 |
Forearm Blood Flow (mL/dL forearm volume/min) | ||||||
Baseline | 8±2 | 10±1 | 5±1 | 4±0† | 9±1 | 6±1† |
5 minutes | 35±5* | 34±4* | 17±1* | 15±1*† | 35±5* | 29±2*† |
Δ | 27±4 | 25±4 | 12±1 | 11±1 | 27±3 | 23±2 |
Forearm Vascular Conductance (mL/dL forearm volume/min/100 mmHg) | ||||||
Baseline | 8±2 | 11±1 | 6±1 | 5±0† | 9±2 | 6±1† |
5 minutes | 37±5* | 37±5* | 19±1* | 16±1*† | 38±5* | 30±2*† |
Δ | 29±4 | 26±4 | 13±1 | 12±1† | 29±4 | 24±2 |
p<0.05 vs Baseline;
p<0.05 vs Control