Table 1.
Baseline descriptive cofactors for patients undergoing ESS with comorbid asthma (n=86)
| Cofactors: | Mean ± SD | Range [LL, UL] | N (%) |
|---|---|---|---|
| Age (years) at enrollment | 47.1 ± 15.6 | [18, 78] | |
| White/Caucasian | 71 (83%) | ||
| African American | 10 (12%) | ||
| Hispanic/Latino | 6 (7%) | ||
| Males | 28 (33%) | ||
| Nasal polyposis | 42 (49%) | ||
| Deviated septum | 25 (29%) | ||
| Turbinate hypertrophy | 7 (8%) | ||
| Allergies (skin prick/RAST confirmed) | 61 (71%) | ||
| AERD | 16 (19%) | ||
| COPD | 7 (8%) | ||
| Depression (self-reported) | 9 (11%) | ||
| Obstructive sleep apnea | 15 (17%) | ||
| Current tobacco use/smoking | 2 (2%) | ||
| Current alcohol use | 19 (22%) | ||
| Previous sinus surgery | 50 (58%) | ||
| Diabetes mellitus (Type I/II) | 9 (11%) | ||
| Corticosteroid dependency (eg. asthma, CRS) | 16 (19%) | ||
| GERD | 20 (23%) | ||
| CRS-specific factors: | |||
| Computed tomography score | 13.2 ± 6.1 | [0, 24] | |
| Endoscopy score | 6.2 ± 3.8 | [0, 14] | |
| SNOT-22 total score (n=86) | 61.6 ± 20.3 | [13, 102] | |
| Rhinologic symptoms | 18.8 ± 6.4 | [2, 30] | |
| Extra-nasal rhinologic symptoms | 10.0 ± 2.9 | [3, 15] | |
| Ear / facial symptoms | 10.2 ± 5.6 | [0, 22] | |
| Psychological dysfunction | 18.7 ± 7.8 | [0, 35] | |
| Sleep dysfunction | 16.3 ± 6.4 | [0, 25] | |
| Asthma-specific factors: | |||
| miniAQLQ total score (n=86) | 4.6 ± 1.4 | [1, 7] | |
| Symptom score | 4.3 ± 1.4 | [1, 7] | |
| Activity score | 5.1 ± 1.5 | [1, 7] | |
| Emotional function score | 4.8 ± 1.7 | [1, 7] | |
| Environmental stimuli score | 4.0 ± 1.6 | [1, 7] | |
| ACT total score (n=77) | 18.4 ± 5.3 | [5, 25] | |
| Uncontrolled asthma (ACT < 20) | 39 (51%) | ||
CRS, chronic rhinosinusitis; SD, standard deviation; N, sample size; LL, lower limit; UL, upper limit; RAST, radioallergosorbent testing; BSIT, Brief Smell Identification Test; AERD, aspirin exacerbated respiratory disease; COPD, chronic obstructive pulmonary disease; miniAQLQ, the Mini Asthma Quality of Life Questionnaire; ACT, the Asthma Control Test survey. SNOT-22, 22-item SinoNasal Outcome Test. BSIT, Brief Smell Identification Test; GERD, gastroesophageal reflux disease.