Table 4.
Comparison of bone histomorphometric measurements for iliac endosteal bone between patients with imcomplete and complete AFF, as well as between AFF patients and premenopausal women
| Incomplete AFF n = 5 |
Complete AFF n = 7 |
p-value* | Normal n = 43 |
Pooled AFF n = 12 |
p-value* | |
|---|---|---|---|---|---|---|
| Static | ||||||
| W.Th (μm) | 31.7 (2.42) | 35.6 (8.61) | 0.418 | 42.4 (8.08) | 34.0 (6.86) | 0.004 |
| OS/BS (%) | 3.44 (2.34) | 3.72 (5.48) | 0.343 | 16.2 (10.7) | 3.60 (4.29) | <0.001 |
| O.Th (μm) | 4.10 (1.74) | 3.38 (2.17) | 0.538 | 8.63 (2.78) | 3.68 (1.95) | <0.001 |
| Ob.S/BS (%) | 1.22 (2.06) | 0.915 (1.35) | 0.755 | 4.40 (3.89) | 1.04 (1.60) | 0.002 |
| Ob.S/OS (%) | 23.6 (26.5) | 16.4 (16.0) | 0.800 | 27.8 (19.2) | 19.4 (20.2) | 0.192 |
| ES/BS (%) | 4.44 (2.07) | 3.06 (5.27) | 0.596 | 9.62 (5.87) | 3.64 (4.15) | <0.001 |
| Oc.S/BS (%) | 1.58 (1.39) | 0.297 (0.420) | 0.041# | 0.486 (0.745) | 0.833 (1.11) | 0.173 |
| Oc.S/NOS (%) | 1.66 (1.46) | 0.329 (0.493) | 0.047# | 0.615 (0.938) | 0.881 (1.17) | 0.287 |
| Dynamic | ||||||
| MS/BS (%) | 1.96 (2.68) | 0.361 (0.955) | 0.268 | 7.02 (6.19) | 1.03 (1.95) | <0.001 |
| MAR (μm) | 0.170 (0.213) | 0.070 (0.185) | 0.268 | 0.492 (0.265) | 0.112 (0.194) | <0.001 |
| BFRs (μm3/μm2/year) | 2.86 (5.17) | 0.645 (1.71) | 0.268 | 15.1 (14.4) | 1.57 (3.55) | <0.001 |
| Ac.f (/year) | 0.018 (0.027) | 0.015 (0.039) | 0.527 | 0.374 (0.364) | 0.016 (0.033) | <0.001 |
Data expressed as mean (SD)
*
p-values significant after a Bonferroni adjustment for 12 tests, i.e. p ≤ 0.05/12 = 0.00417 are shown in bold
#
p-values not significant after a Bonferroni correction for 12 tests, i.e. p ≤ 0.05/12 = 0.00417.