Table 3.
Confirmed and new biological activities of azo compounds (22–39) derived from actinomycetes
| No. | Activity reviewed | Activities confirmed (Pa) | Additional predicted activities (Paa) |
|---|---|---|---|
| 22 | Antibiotic antifungal | – | Antineoplastic (0.845) Phobic disorders treatment (0.775) Antiviral (picornavirus) (0.735) |
| 23 | Antibiotic | – | Antineoplastic (0.781) Phobic disorders treatment (0.750) Antiviral (arbovirus) (0.565) |
| 24 | Antibacterial antineoplastic | Antineoplastic (0.923) Antibacterial (0.613) |
Antifungal (0.633) Genital warts treatment (0.648) Spasmolytic, urinary (0.605) |
| 25 | Antibacterial antineoplastic | Antineoplastic (0.927) Antibacterial (0.573) |
Spasmolytic, urinary (0.687) Genital warts treatment (0.648) Immunosuppressant (0.596) |
| 26 | Antibiotic antifungal | Antifungal (0.640) Antibacterial (0.474) |
Hepatic disorders treatment (0.778) Antineoplastic (0.763) Antieczematic (0.717) |
| 27 | Antibiotic antifungal | Antifungal (0.658) Antibacterial (0.514) |
Hepatic disorders treatment (0.793) Antiviral (arbovirus) (0.771) Antineoplastic (0.779) |
| 28 | Antineoplastic antibiotic cytotoxic ornithine decarboxylase inhibitor | Anti-Helicobacter pylori (0.995) | Kidney function stimulant (0.636) Antieczematic (0.644) Preneoplastic conditions treatment (0.590) |
| 29 | Antineoplastic antibiotic | – | Anti-Helicobacter pylori (0.994) Preneoplastic conditions treatment (0.513) |
| 30 | Microtubule inhibitor | – | Anti-Helicobacter pylori (0.893) Antieczematic (0.751) Fibrinolytic (0.638) |
| 31 | Microtubule inhibitor | – | Anti-Helicobacter pylori (0.915) Preneoplastic conditions treatment (0.670) Kidney function stimulant (0.654) |
| 32 | Not studied | – | Antiseborrheic (0.793) Antiinflammatory (0.780) Hemostatic (0.668) |
| 33 | Nematocide | – | Antiseborrheic (0.793) Antiinflammatory (0.780) Hemostatic (0.668) |
| 34 | Nematocide | – | Anti-Helicobacter pylori (0.939) Antiseborrheic (0.717) Alopecia treatment (0.650) |
| 35 | Not studied | – | Antiinflammatory (0.714) Phobic disorders treatment (0.682) Preneoplastic conditions treatment (0.617) |
| 36 | Not studied | – | Anti-Helicobacter pylori (0.932) Preneoplastic conditions treatment (0.605) |
| 37 | Nematocide cytotoxic | – | Anti-Helicobacter pylori (0.932) Phobic disorders treatment (0.672) Preneoplastic conditions treatment (0.568) |
| 38 | Not studied | – | Apoptosis agonist (0.935) Antineoplastic (0.788) Alopecia treatment (0.653) |
| 39 | Not studied | – | Apoptosis agonist (0.920) Antineoplastic (0.724) Antiviral (arbovirus) (0.622) |
aOnly activities with Pa > 0.5 are shown