Table 1.
Characteristic | Patients, n = 28 |
---|---|
Age at start | |
Years | 69 (10) |
Sex | |
Male | 16 (57 %) |
Female | 12 (43 %) |
WHO performance status | |
0 | 12 (43 %) |
1 | 13 (46 %) |
2 | 1 (4 %) |
Unknown | 2 (7 %) |
c-KIT mutation | |
Wild type | 5 (18 %) |
Exon 9 | 6 (21 %) |
Exon 11 | 12 (43 %) |
Exon 13 | 3 (11 %) |
Unknown | 2 (7 %) |
Treatment setting | |
Neoadjuvant | 11 (39 %) |
Adjuvant | 5 (18 %) |
Palliative | 12 (43 %) |
Dose at start | |
300 mg QD | 1 (4 %) |
400 mg QD | 26 (93 %) |
800 mg QD | 1 (4 %) |
All values are presented as n (%) or as mean (standard deviation)
c-KIT KIT proto-oncogene receptor tyrosine kinase, QD once daily, WHO World Health Organization