Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 17;12:18. doi: 10.1186/s13000-017-0609-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 4 — Expression pattern of CK7, CK19, p16, and HR HPV in CIN3. HE staining shows representative CIN3s developing in the ectocervix (CIN3#12) (a), transformation zone (CIN3#21) (b), and SCJ (CIN3#23) (c), respectively. CIN3#12 shows patchy staining of CK7 in the upper layer (d), patchy staining of CK19 in the lower layer (g), diffuse staining of p16 (j), mixture of episomal and integrated HPV with remarkable episomal form in the upper layer (m). CIN3#21 and CIN3#23 show diffuse staining of CK7 (e and f), CK19 (h and i), and p16 (k and l). HPV is present in integrated form in CIN3#21 (n) and mixed episomal and integrated form in CIN3#23 (o). Original magnifications: x400