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. Author manuscript; available in PMC: 2017 Feb 18.
Published in final edited form as: Sci Transl Med. 2016 May 4;8(337):337ra63. doi: 10.1126/scitranslmed.aaf2326

Fig. 7. Comparison of bile acid B in dried blood spots with cholestane-3β,5α,6β-triol in plasma.

Fig. 7

(A) Correlation of bile acid B in dried blood spots with cholestane-3β,5α,6β-triol in plasma (n = 47), r = 0.59, P < 0.0001. x, bile acid cutoff for NPC1 carriers and controls; y, cholestane-3β,5α,6β-triol cutoff for NPC1 carriers; z, cholestane-3β,5α,6β-triol cutoff for controls. (B) The inset bounded by the dotted purple line in panel (A) has been expanded to more clearly compare assay specificity.