Table 1.
Cohort characteristics and univariate analysis of celiac disease cases versus non-cases.
| All cases | CD | Controls | P value | |
|---|---|---|---|---|
| N (%) | 3555 | 517 (15) | 3038 (85) | - |
| Girls (%) | 2010 (57) | 330 (64) | 1680 (55) | <0.003 |
| Under 2 years old (%) | 273 (8) | 27 (5) | 246 (8) | 0.023 |
| Mean age (SD) | 10 (5) | 9.4 (4.8) | 10.0 (5.3) | 0.016 |
| Low serum IgAa (%) | 222 (6) | 34 (7) | 188 (6) | 0.736 |
| Trisomy 21 (%) | 58 (2) | 17 (3) | 41 (2) | 0.001 |
| Type I DM (%) | 170 (5) | 88 (17) | 82 (3) | <0.003 |
| BMI Z score (SD) | −0.13 (1.4) | −0.14 (1.4) | −0.12 (1.4) | 0.78 |
BMI, body mass index; DM, diabetes mellitus; IgA, immunoglobulin A;
a
serum IgA value flaged as “low”