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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Acta Biomater. 2017 Jan 4;50:417–427. doi: 10.1016/j.actbio.2017.01.005

Figure 8.

Figure 8

Prophylactic antitumor effect of vaccinating mice with different polyanhydride/OVA formulations ± soluble CpG ODN. Mice were primed (day 0) and boosted (day 7) with indicated treatments (I to VII) before being challenged with tumor cells (day 35). Tumor growth was monitored regularly post challenge for up to 2 months. Each curve represents the tumor growth for each individual mouse. Tumor volumes from each group were statistically compared at day 16 (VIII). Asterisk symbol (*) refers to the statistically significant difference/s between the naïve and other vaccinated groups unless otherwise specified. Data are plotted as mean ± SD, n = 5. *p<0.05, **p<0.01, ***p<0.001.