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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Heart Lung Transplant. 2016 Aug 20;36(3):340–354. doi: 10.1016/j.healun.2016.08.011

Figure 5. RhoA deletion down-regulates expression of CX3CR1 receptor in blood and bone marrow monocytes and peritoneal macrophages.

Figure 5

(A–D) Flow cytometry analysis of monocytes in blood and bone marrow shows statistically highly significant decrease in CXC3R1 expression level in RhoA-deleted mice. (E, F) Flow cytometry analysis of CCR2 expressing monocytes in blood shows slight difference (at the border of being significant) between wild type and RhoA- deleted mice. (G, H) Flow cytometry analysis of peritoneal macrophages shows statistically highly significant decrease in CX3CR1 expression level in RhoA- deleted macrophages. (I) The level of CX3CR1 mRNA, as measured by RTPCR, is highly and statistically significantly upregulated in RhoA-deleted macrophages. (J, K) Flow cytometry analysis of peritoneal macrophages shows no significant difference between expression levels of CCR2 in wild type and RhoA- deleted macrophages. 3 mice from each experimental group were used.