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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Pharmacol Res. 2016 Nov 17;117:192–217. doi: 10.1016/j.phrs.2016.11.012

Fig. 1. Chemical structures of ART and its derivatives.

Fig. 1

ART (parent drug), DHA (active metabolite), arteether (oil-soluble derivative), artemether (oil-soluble derivative), artesunate (water soluble derivative), arterolane and artefenomel (trioxolane), and RKA 216 and 182 (tetraoxanes).