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PA28αOE decreased GFPdgn accumulation in the hearts of diabetic mice. GFPdgn transgene was introduced into CTL and PA28αOE mice. Diabetes was then induced by STZ injection into the resultant CTL/GFPdgn and PA28αOE/GFPdgn mice 8 weeks after STZ injection. A–B, Western blots (A) of the indicated proteins in myocardial homogenates and the quantification (B) of GFPdgn proteins. n=3–4 mice per group.
