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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Nov 30;102:53–60. doi: 10.1016/j.yjmcc.2016.11.013

Figure 7.

Figure 7

PA28αOE improved cardiac function in diabetic mice. Invasive hemodynamic measurements were obtained in CTL and PA28aOE mice 8 weeks after STZ injection. Results of pressure-volume (PV) loop analyses showing measures of systolic (AD) and diastolic (E–H) function. dP/dt max, maximal dP/dt; Pes, end-systolic pressure; Ves, end-systolic volume; EF, ejection fraction; dP/dt min, minimal dP/dt; Ped, end-diastolic pressure; Ved, end-diastolic volume; Tau, the load-independent isovolumic relaxation constant. N=7–9 mice per group. Data are expressed as Mean+SEM. **P<0.01 versus CTL; #P<0.05, ##P<0.01 versus CTL+STZ, respectively.