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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: J Biomed Inform. 2017 Jan 10;66:171–179. doi: 10.1016/j.jbi.2017.01.004

Table 4.

Best fitting generalized estimating equations Type III model effects and parameter estimates, predicting diagnostic accuracy.

Effect B SE Odds
Ratio
Exp(B)
95%
CI
Wald
χ2(df)
p-
value
Type III Model Effects   
  Case Consensus Diagnosis 20.69(3) <.001
  Case Breast Density 8.17(1) .004
  Case Difficulty Rating 20.06(1) <.001
  Pathologist Experience 18.58(1) <.001
  Fixation Durations 6.84(1) .009
  Fixations within versus
outside ROIs
11.24(1) .001
  Zoom Behavior 3.08(1) .079
  Number of Fixations 2.13(1) .144
  Pathologist Experience ×
Consensus Diagnosis
9.02(3) .029
  Pathologist Experience ×
Zoom Behavior
3.49(1) .062
Model Parameter Estimates
  Case Consensus Diagnosis
(reference: benign)
    Atypia −.629 .357 .533 (.265, 1.07) 3.10(1) .078
    DCIS −.588 .384 .555 (.262, 1.18) 2.35(1) .125
    Invasive 1.91 .614 6.72 (2.02, 22.4) 9.64(1) .002
  Case Breast Density
(reference: BI-RADS 1–2)
    BI-RADS 3–4 .813 .285 2.26 (1.29, 3.94) 8.17(1) .004
  Case Difficulty Rating −.695 .155 .499 (.368, .677) 20.06(1) <.001
  Pathologist Experience −.054 .279 .947 (.547, 1.64) .038(1) .846
  Fixation Durations .201 .077 1.22 (1.05, 1.42) 6.84(1) .009
  Fixations in versus outside
ROIs
.420 .125 1.52 (1.19, 1.94) 11.24(1) .001
  Zoom Behavior −.207 .118 .813 (.645, 1.03) 3.08(1) .079
  Number of Fixations −.166 .114 .847 (.677, 1.06) 2.13(1) .144
  Pathologist Experience ×
Consensus Diagnosis
    Atypia .590 .335 1.80 (.936, 3.48) 3.11(1) .078
    DCIS .910 .328 2.49 (1.31, 4.72) 7.72(1) .005
    Invasive 1.21 .540 3.37 (1.17, 9.71) 5.05(1) .025
  Pathologist Experience ×
Zoom Behavior
−.273 .146 .761 (.572, 1.01) 3.49(1) .062