Table 2.
The table shows the reading and results of glimepiride sublingual tablet formulation.
| Name of the test | Reading | Comments | |||
|---|---|---|---|---|---|
| Amaryl | F5 (new glimepiride) | ||||
| Assay | 100.5% | 103% | Conformed | ||
|
| |||||
| Friability | 0.02% | 0.40% | Conformed | ||
|
| |||||
| Weight variation | 1 | 0.1669 | 0.116 | Conformed | |
| 2 | 0.168 | 0.116 | |||
| 3 | 0.1676 | 0.116 | |||
| 4 | 0.167 | 0.115 | |||
| 5 | 0.1687 | 0.115 | |||
| 6 | 0.1673 | 0.115 | |||
| 7 | 0.168 | 0.113 | |||
| 8 | 0.1688 | 0.115 | |||
| 9 | 0.1679 | 0.114 | |||
| 10 | 0.169 | 0.114 | |||
| 11 | 0.1672 | 0.113 | |||
| 12 | 0.169 | 0.115 | |||
| 13 | 0.1673 | 0.117 | |||
| 14 | 0.1684 | 0.117 | |||
| 15 | 0.169 | 0.115 | |||
| 16 | 0.1685 | 0.111 | |||
| 17 | 0.1669 | 0.111 | |||
| 18 | 0.1674 | 0.111 | |||
| 19 | 0.1678 | 0.115 | |||
| 20 | 0.1678 | 0.114 | |||
| Average | 0.167925 | 0.1141 | |||
|
| |||||
| Number | Reading | Number | Reading | ||
|
| |||||
| Hardness | 1 | 5.35 | 1 | 3.8 | Not conformed |
| 2 | 4.28 | 2 | 4.5 | Conformed | |
| 3 | 4.06 | 3 | 4.3 | Conformed | |
| 4 | 3.81 | 4 | 4.3 | Conformed | |
| 5 | 5.3 | 5 | 3.5 | Not conformed | |
|
| |||||
| Disintegration time | 1.15 minutes | 21 seconds | Conformed | ||