Fig. 9.
Effects of graded doses of testosterone (T; 10−10 to 10−7 M) or vascular endothelial growth factor (VEGF; 0.1 to 10 ng/ml) on numbers of total and healthy follicles in ovarian cortical pieces isolated from late term (5–8 mo. gestation) fetuses and cultured for 10 days (white bars). Secondary follicles were not observed in freshly isolated cortical pieces (Day 0). Con: day 10 controls. Within each panel, means (bars; mean per section ± SEM) with no common letters are significantly different (P < 0.05; n = 3 fetuses). ND: not detected. (Data are from Yang & Fortune 2006 and Yang & Fortune 2007.)