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. Author manuscript; available in PMC: 2018 Jan 3.
Published in final edited form as: Anal Chem. 2016 Nov 18;89(1):157–188. doi: 10.1021/acs.analchem.6b04260

Figure 8.

Figure 8

Representative examples of hybrid nanopore platforms. (Top) Carbon nanotubes (CNTs) within a lipid bilayer. (a) Schematic depiction of ssDNA translocation event through a CNT porin in the lipid bilayer. (b) Representative current traces in the absence (top) and presence (bottom) of ssDNA. (a, b) Reproduced from Geng, J.; Kim, K.; Zhang, J.; Escalada, A.; Tunuguntla, R.; Comolli, L. R.; Allen, F. I.; Shnyrova, A. V.; Cho, K. R.; Munoz, D. Nature 2014 514, 612–615 (ref 83), with permission from Nature Publishing Group. (Bottom) Membrane patch-ion channel probe. (c) Instrumental setup for dual-barrel ion channel probe-SICM measurements. (d) Current–time (I–T) traces recorded with the ICP barrel close (top) and far (bottom) from surface substrate. (c, d) Reproduced from Shi, W.; Zeng, Y.; Zhou, L.; Xiao, Y.; Cummins, T. R.; Baker, L. A. Faraday Discuss 2016, DOI: 10.1039/C6FD00133E (ref 80), with permission of The Royal Society of Chemistry.