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. 2017 Feb 20;7:13. doi: 10.3389/fonc.2017.00013

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Copyright © 2017 Faria, Morris, Silva, Fonseca, Forget, Castro and Fontes.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of the number of studies according to the approach given by the authors. (A) Based on the use of targeted proteomics dedicated to different types of cancer, further grouped into the clinical application of each biomarker; (B) the clinical application of different biomarkers found in within the studied cancer types; (C) distribution of the studies using different sample types according to the clinical application of the biomarkers. These charts were based on data from all studies included in this review that focused on the analysis of cancer-related samples, either from human, or from other species or in vitro tests.