Table 8.
Summary of studies with relatively large cohort of patients who underwent hepatectomy for liver metastasis from sarcoma
| Ref. | Year | Period | No. of patients | MST (mo) | 3-ysr (%) | 5-ysr (%) | Factors associated with worse overall survival |
| Lang et al[48] | 2000 | 1982-1996 | 26 (including 9 second, 2 third resection) | 32 (R0 first resection), 21 (R1,2 resection) | NR | 13 | NR |
| DeMatteo et al[26]1 | 2001 | 1982-2000 | 561 | 391 | 501 | 301 | Time to liver metastasis from the primary tumor diagnosis ≤ 24 mo |
| Pawlik et al[49] | 2006 | 1996-2005 | 53 (35Hx, 18RF + Hx, and 13RF), (including 36 GISTs) | 472 | 652 | 272 | Non-GIST |
| Marudanayagam et al[50] | 2011 | 1997-2009 | 361 (including 5 GISTs) | 24 | 48 | 32 | Primaly leiomyosarcoma |
| Groeschl et al[13]3 | 2012 | 1990-2009 | 98 | 72 | 60 | 32 | NR |
| Zhang et al[51] | 2015 | 2000-2009 | 27 | NR | NR | 46 | Interval from primary tumor diagnosis ≤ 24 mo, extrahepatic disease, positive margins |
1
Including some patients with GIST before 1993, GISTs were considered as leiomyosarcomas;
2
Including results of RF and patients with GIST;
3
As a part of the report of on-colorectal non-neuroendocrine liver metastases. GIST: Gastrointestinal stromal tumor; MST: Median survival time; ysr: Year survival rate; NR: Not reported; Hx: Hepatectomy; RF: Radiofrequency ablation.