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. 2017 Feb 20;7:42800. doi: 10.1038/srep42800

Table 1. Upregulated proteins identified in the proteomics screen which satisfied the criteria of a fold-change of >1.5 and P-value < 0.05.

Majority protein IDs Protein names Gene names P value (−Log10) Difference (Log2) Unique peptides Mol. weight [kDa]
Q8K298 Actin-binding protein anillin Anln 5.145 2.026 18 122.79
Q9CYW4 Haloacid dehalogenase-like hydrolase domain-containing protein 3 Hdhd3 1.899 1.633 4 28.027
Q3TFD2 Lysophosphatidylcholine acyltransferase 1 Lpcat1 2.301 1.605 3 54.649
Q78XF5 Oligosaccharyltransferase complex subunit OSTC Ostc 3.778 1.604 2 16.815
Q9D3D9 ATP synthase subunit delta, mitochondrial Atp5d 2.552 1.560 5 17.6
Q9CR41 Huntingtin-interacting protein K Hypk 2.786 1.560 4 14.679
Q05CN2 Ribosomal RNA processing protein 1 homolog A Rrp1 1.762 1.529 4 42.904
Q9CXG3 Peptidyl-prolyl cis-trans isomerase-like 4 Ppil4 2.440 1.485 10 57.23
Q0KL02 Triple functional domain protein Trio 2.018 1.398 7 288.71
Q80ZX0 Protein Sec24b Sec24b 2.144 1.358 9 135.55
Q5XF89 Probable cation-transporting ATPase 13A3 Atp13a3 2.296 1.339 3 137.47
Q9CR27 WASH complex subunit CCDC53 Ccdc53 2.265 1.323 3 21.092
F2Z4B3 Cyclin-dependent kinase 2-associated protein 1 Cdk2ap1 2.562 1.258 3 9.6308
Q4KML4 Costars family protein ABRACL Abracl 4.853 1.254 5 9.0303
P16254 Signal recognition particle 14 kDa protein Srp14 3.115 1.250 6 12.51
Q8CHT1 Ephexin-1 Ngef 4.329 1.243 6 71.415
Q99LC8 Translation initiation factor eIF-2B subunit alpha Eif2b1 1.667 1.217 7 33.816
Q3TME9 Tyrosine-protein kinase Fer Fer 3.260 1.209 4 45.071
Q6ZQK0 Condensin-2 complex subunit D3 Ncapd3 3.285 1.189 12 169.43
Q8BW84 Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial Pet112 3.543 1.180 5 61.509
E9Q555 E3 ubiquitin-protein ligase RNF213 Rnf213 2.675 1.138 18 584.49
Q8R5C5 Beta-centractin Actr1b 1.997 1.098 6 42.281
Q9DCJ5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 Ndufa8 3.935 1.098 5 19.992
Q8BGB7 Enolase-phosphatase E1 Enoph1 2.729 1.096 3 25.358
Q52L97 Importin subunit alpha Kpna2 4.766 1.053 14 57.927
P62077 Mitochondrial import inner membrane translocase subunit Tim8 B Timm8b 4.695 1.034 3 9.2864
Q99LT0 Protein dpy-30 homolog Dpy30 3.094 1.015 4 11.213
E9PY48 Condensin-2 complex subunit H2 Ncaph2 1.970 1.010 4 65.309
Q9EPL8 Importin-7 Ipo7 4.506 0.978 20 119.49
Q9DAS3 Dynein light chain Tctex-type 1 Dynlt1f 3.252 0.960 3 11.625
Q91WK1 SPRY domain-containing protein 4 Spryd4 2.463 0.937 7 23.275
Q6P4T3 Eyes absent homolog 3 Eya3 2.519 0.924 13 57.854
Q9D1R2 Protein KTI12 homolog Kti12 1.877 0.905 4 38.444
D5MCW4 Protein CutA Cuta 3.344 0.897 3 16.453
Q543N6 Serine/threonine-protein phosphatase 2 A activator Ppp2r4 2.280 0.897 15 36.71
Q9CRT8 Exportin-T Xpot 2.742 0.888 15 109.73
A2AEB4 Mortality factor 4-like protein 2 Morf4l2 2.734 0.886 6 22.919
Q9CQK7 RWD domain-containing protein 1 Rwdd1 2.170 0.884 6 27.785
D3YYC2 Dr1-associated corepressor Drap1 3.189 0.863 4 17.587
Q8CC06 Integrin alpha-6 Itga6 2.066 0.859 12 119.6
Q3UB06 SRSF protein kinase 1 Srpk1 4.142 0.856 10 73.088
Q9D7A8 Armadillo repeat-containing protein 1 Armc1 2.063 0.851 4 31.246
Q9CZ30 Obg-like ATPase 1 Ola1 3.529 0.846 21 44.729
P08030 Adenine phosphoribosyltransferase Aprt 3.618 0.844 12 19.724
Q5SSZ5 Tensin-3 Tns3 3.978 0.840 1 58.725
Q3UTL4 High affinity cationic amino acid transporter 1 Slc7a1 2.364 0.835 3 67.107
Q8VDF2 E3 ubiquitin-protein ligase UHRF1 Uhrf1 3.938 0.829 20 87.555
Q9CPY1 39 S ribosomal protein L51, mitochondrial Mrpl51 3.421 0.822 4 15.103
Q6PE15 Mycophenolic acid acyl-glucuronide esterase, mitochondrial Abhd10 2.757 0.821 6 33.04
Q548K2 Alcohol dehydrogenase class 4 mu/sigma chain Adh7 2.849 0.819 9 39.837
Q9CY16 28 S ribosomal protein S28, mitochondrial Mrps28 3.494 0.817 7 20.52
G3XA18 N-acylethanolamine-hydrolyzing acid amidase Naaa 1.903 0.807 3 39.803
Q8R5H1 Ubiquitin carboxyl-terminal hydrolase 15 Usp15 4.365 0.803 28 112.32
Q3UMQ8 H/ACA ribonucleoprotein complex non-core subunit NAF1 Naf1 2.307 0.802 3 53.245
O70591 Prefoldin subunit 2 Pfdn2 4.651 0.798 7 16.534
Q8C845 EF-hand domain-containing protein D2 Efhd2 1.873 0.795 7 26.8
Q6P9R1 ATP-dependent RNA helicase DDX51 Ddx51 3.675 0.791 14 70.367
E9PUB0 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Arap1 2.705 0.780 8 83.2
Q7TMR0 Lysosomal Pro-X carboxypeptidase Prcp 5.910 0.777 13 55.026
Q9JJ44 DUTPase Dut 3.584 0.777 7 17.414
Q921M8 Ubiquitin carboxyl-terminal hydrolase Usp4 1.494 0.769 20 103.75
E9PX53 Serine/threonine-protein phosphatase 4 regulatory subunit 1 Ppp4r1 1.509 0.765 8 104.5
Q9D046 Centrin-3 Cetn3 2.665 0.762 3 19.447
Q99LZ3 DNA replication complex GINS protein SLD5 Gins4 1.888 0.760 4 25.961
Q9JKB3 Y-box-binding protein 3 Ybx3 3.254 0.757 1 38.813
Q6PDL0 Cytoplasmic dynein 1 light intermediate chain 2 Dync1li2 2.409 0.754 9 54.218
Q80 × 98 DEAH (Asp-Glu-Ala-His) box polypeptide 38 Dhx38 2.570 0.754 19 140.62
Q561N4 Ubiquitin-conjugating enzyme E2 L3 Ube2l3 1.881 0.746 1 17.861
Q8C6I2 Succinate dehydrogenase assembly factor 2, mitochondrial Sdhaf2 3.361 0.745 6 19.431
Q8K2A7 Integrator complex subunit 10 Ints10 2.772 0.739 10 82.019
Q8K4L0 ATP-dependent RNA helicase DDX54 Ddx54 1.902 0.739 13 97.747
Q5SW19 Clustered mitochondria protein homolog Cluh 3.374 0.736 13 148.07
Q6A009 E3 ubiquitin-protein ligase listerin Ltn1 2.232 0.729 10 198.92
Q545F0 Macrophage migration inhibitory factor Mif 3.086 0.728 9 12.504
Q9DBY0 Forkhead box protein P4 Foxp4 3.890 0.722 7 72.758
Q8R404 Protein QIL1 Qil1 2.812 0.722 6 13.373
Q86Y56 Dynein assembly factor 5, axonemal Heatr2 1.698 0.722 6 93.85
Q3TBW2 39 S ribosomal protein L10, mitochondrial Mrpl10 2.758 0.719 5 29.395
E9PWB1 Pleckstrin homology-like domain family B member 1 Phldb1 3.099 0.716 32 145.04
P70698 CTP synthase 1 Ctps1 3.766 0.715 29 66.682
Q3UMC0 Spermatogenesis-associated protein 5 Spata5 1.550 0.710 5 97.255
Q922Y1 UBX domain-containing protein 1 Ubxn1 3.403 0.709 8 33.572
Q8K4F6 Putative methyltransferase NSUN5 Nsun5 2.148 0.708 6 51.029
Q64261 Cyclin-dependent kinase 6 Cdk6 6.123 0.706 5 37.028
J3QP71 Basigin Bsg 2.028 0.703 7 21.602
Q99M31 Heat shock 70 kDa protein 14 Hspa14 3.418 0.701 13 54.65
Q63870 Collagen alpha-1(VII) chain Col7a1 3.142 0.699 13 295.23
A2A6Q5 Cell division cycle protein 27 homolog Cdc27 2.122 0.696 6 91.841
Q9CRA5 Golgi phosphoprotein 3 Golph3 1.933 0.691 9 33.752
Q9JIK5 Nucleolar RNA helicase 2 Ddx21 5.098 0.690 59 93.55
Q6ZPJ3 Ubiquitin-conjugating enzyme E2 O Ube2o 2.910 0.689 7 140.83
Q3UVH2 Tyrosine-protein kinase CSK Csk 2.833 0.687 12 50.73
Q63829 COMM domain-containing protein 3 Commd3 2.101 0.680 5 22.037
Q9R0H0 Peroxisomal acyl-coenzyme A oxidase 1 Acox1 2.545 0.675 14 74.717
Q3UA06 Pachytene checkpoint protein 2 homolog Trip13 1.747 0.670 8 48.376
Q8R3P6 von Willebrand factor A domain-containing protein 9 Vwa9 2.231 0.670 7 57.236
Q921Q7 Ras and Rab interactor 1 Rin1 1.329 0.664 4 83.013
P62488 DNA-directed RNA polymerase II subunit RPB7 Polr2g 2.233 0.663 7 19.294
Q6NS79 Protein diaphanous homolog 1 Diap1 2.186 0.662 16 135.84
Q8BL74 General transcription factor 3 C polypeptide 2 Gtf3c2 2.088 0.659 6 100.27
J3QMC5 Midasin Mdn1 2.800 0.659 41 629.58
Q91VJ4 Serine/threonine-protein kinase 38 Stk38 1.602 0.659 4 54.174
Q8R126 Gltscr2 protein Gltscr2 2.771 0.658 7 54.506
Q3U8P5 Vacuolar protein sorting-associated protein 4B Vps4b 3.743 0.656 8 49.464
F8VQ54 Endoribonuclease Dicer Dicer1 1.684 0.655 7 215.77
P70444 BH3-interacting domain death agonist Bid 1.761 0.650 5 21.951
Q8C079 Striatin-interacting protein 1 Strip1 1.444 0.648 7 86.884
Q9EQ80 NIF3-like protein 1 Nif3l1 2.376 0.644 10 41.745
E9QAP7 Protein Taf Taf4a 1.489 0.643 5 73.137
Q3THE6 Ferritin Ftl1 3.246 0.628 2 20.695
Q3UUQ7 GPI inositol-deacylase Pgap1 2.451 0.628 2 104.58
Q3THG5 Cyclin-dependent kinase 7 Cdk7 1.353 0.626 4 38.968
Q9D071 MMS19 nucleotide excision repair protein homolog Mms19 1.478 0.626 8 97.458
Q9QY06 Unconventional myosin-IXb Myo9b 3.626 0.620 11 238.83
A3KMJ8 Prefoldin subunit 3 Vbp1 3.410 0.619 9 21.963
Q6ZQH8 Nucleoporin NUP188 homolog Nup188 2.879 0.618 21 196.69
Q9DC50 Peroxisomal carnitine O-octanoyltransferase Crot 1.812 0.617 6 70.264
Q5PPR2 Exocyst complex component 1 Exoc1 1.615 0.616 5 100.19
Q9CZD3 Glycine–tRNA ligase Gars 3.168 0.609 38 81.877
Q9CSZ1 BTB/POZ domain-containing protein KCTD5 Kctd5 1.377 0.606 2 18.877
Q8BVG4 Dipeptidyl peptidase 9 Dpp9 2.135 0.603 10 98
A6H5Z3 Exocyst complex component 6B Exoc6b 1.806 0.601 5 94.128
F8VQJ3 Laminin subunit gamma-1 Lamc1 3.495 0.601 24 177.19
Q9D358 Low molecular weight phosphotyrosine protein phosphatase Acp1 1.924 0.600 7 18.192
Q80VI1 E3 ubiquitin-protein ligase TRIM56 Trim56 2.562 0.598 10 79.512
Q3UHB1 5-nucleotidase domain-containing protein 3 Nt5dc3 2.245 0.598 11 63.17
P11440 Cyclin-dependent kinase 1 Cdk1 3.618 0.598 14 34.106
Q9JJY4 Probable ATP-dependent RNA helicase DDX20 Ddx20 1.349 0.597 8 91.709
Q99K58 Fibulin-2 Fbln2 1.933 0.596 6 126.46
Q8WTY4 Anamorsin Ciapin1 2.119 0.596 9 33.429
Q8BJ03 Cytochrome c oxidase assembly protein COX15 homolog Cox15 1.314 0.595 3 44.005
Q3TKX4 Probable ATP-dependent RNA helicase DDX52 Ddx52 2.903 0.595 20 67.129
Q9DB96 Neuroguidin Ngdn 2.196 0.594 5 35.658
Q5SWU9 Acetyl-CoA carboxylase 1 Acaca 3.318 0.593 26 265.25
P46664 Adenylosuccinate synthetase isozyme 2 Adss 3.358 0.591 25 50.02
Q6WKZ8 E3 ubiquitin-protein ligase UBR2 Ubr2 2.034 0.586 18 199.2