Figure 4. RNA-seq analyses detected gene expression changes in Rp9 mutant cells.
(A) Volcano plot showing genes differentially expressed in Rp9-KI compared with control group. Red dots show the 784 genes with a |log2FC| > 1 and FDR < 0.05. (B) Volcano plot showing genes differentially expressed in Rp9-KO compared with control group. Red dots show the 934 genes with a |log2FC| > 1 and FDR < 0.05. (C) Overlap of differential gene expression betweenRp9-KI and Rp9-KO group. Red dots show the Fscn2 gene down-regulated in both groups. (D) Heatmaps present RP associated gene expression in Rp9-KI and Rp9-KO group.