Table 1.
| Group comparison1 | PTBsigUp | PTBsigDn | ||||
|---|---|---|---|---|---|---|
| NES2 | FDR3 | Correlation3 | NES2 | FDR3 | Correlation3 | |
| Neut_PTB versus Neut_HC | 3.64 | 0.000 | Positive | −1.97 | 0.000 | Negative |
| Mono_PTB versus Mono_HC | 3.53 | 0.000 | Positive | −1.92 | 0.000 | Negative |
| CD4_PTB versus CD4_HC | 2.93 | 0.000 | Positive | −1.82 | 0.000 | Negative |
| CD8_PTB versus CD8_HC | 2.66 | 0.000 | Positive | −1.71 | 0.000 | Negative |
1Neut_PTB versus Neut_HC = ranked relative expressions of genes of neutrophils in PTB patients compared to neutrophils in HC donors. Similar explanations apply for the other three group comparisons. 2(+) NES for positive correlation indicating that signature genes were overrepresented at the higher end of a ranked gene list; (−) NES for negative correlation indicating that signature genes were overrepresented at the lower end of a ranked gene list. 3A FDR of 0.05 or lower was regarded as statistically significant for NES (“positive” or “negative”).