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. 2017 Feb 20;7:42939. doi: 10.1038/srep42939

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Copyright © 2017, The Author(s)

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Comparison of cell proliferation of deep endometriotic stromal cells DES (n = 14), endometrial stromal cells of patients with endometriosis (EES) derived from the proliferative phase (EES-P) (n = 10), EES derived from the secretory phase (EES-S) (n = 6) and EES derived from the menstrual phase (EES-M) (n = 5) grown on PGS of varying stiffness (2 (A) or 30 kPa (B)) or plastic (C) treated with combination U0126 and MK2206. Dose 1: U0126 (15 μM) and MK2206 (4.5 μM). Dose 2: U0126 (30 μM) and MK2206 (9 μM). P: EES-P. S: EES-S. M: EES-M. Numerical values are presented as box and whisker plots showing medians and the smallest and largest data points ≤1.5 × IQR from the 25th and 75th percentiles, respectively.