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. 2017 Feb 20;7:42902. doi: 10.1038/srep42902

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The phylogenetics assay was performed on VP1 protein sequences from representative HEVs using ClustalW, and the results were visualized using MEGA5. The red branch indicates HEV-A, the blue branch indicates HEV-B, the green branch indicates HEV-C and the black branch indicates HEV-D. Viruses labeled with red dots can be inhibited by suramin, and viruses labeled with black dots are resistant to suramin. Suramin potency was not examined in the present study for the viruses without a circle.