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. 2017 Feb 20;7:42902. doi: 10.1038/srep42902

Table 3. Suramin inhibition of HEVs.

Group Name Strain Viral load in 0 μM suramin Viral load reduction
10 μM suramin 100 μM suramin
A CV-A2 Fleetwood 6.5 log10 TCID50/ml 0.3 log10 TCID50/ml 3.4 log10 TCID50/ml
CV-A3 Olson 4.1 log10 TCID50/ml 1.4 log10 TCID50/ml 4.1 log10 TCID50/ml
CV-A10 Kowalik 6.1 log10 PFU/ml 2.7 log10 PFU/ml 6.1 log10 PFU/ml
CV-A12 Texas 12 4.8 log10 TCID50/ml −0.2 log10 TCID50/ml 4.8 log10 TCID50/ml
CV-A16* shzh05-1 9.7 log10 TCID50/ml 2.0 log10 TCID50/ml >7.0 log10 TCID50/ml
EV-A71 Fuyang 573 6.1 log10 TCID50/ml 4.8 log10 TCID50/ml 6.1 log10 TCID50/ml
EV-A71 SH12-276 4.3 log10 TCID50/ml 0.5 log10 TCID50/ml 2.3 log10 TCID50/ml
B CV-A9 RO-609/4/80 5.9 log10 TCID50/ml 0.4 log10 TCID50/ml 2.9 log10 TCID50/ml
CV-B3 Nancy n.a. no no
CV-B4 J.V.B. Benschoten n.a. no no
ECHO20 JV-1 3.6 log10 TCID50/ml 0.7 log10 TCID50/ml 0.7 log10 TCID50/ml
ECHO25 JV-4 2.5 log10 TCID50/ml 0.0 log10 TCID50/ml −0.2 log10 TCID50/ml
C Poliovirus 1 Sabin-1 n.a. no no
Poliovirus 2 Sabin-2 n.a. no no
Poliovirus 3 Sabin-3 n.a. no no
Poliovirus 1 Mahoney 91 n.a. no no
Poliovirus 3 P3/Leon/37 n.a. no no
D EV-D68 Fermon n.a. no no

*Tested in RD cells based on TCID50 titration, which was published in previous study12. n.a.: Data not available. no: Suramin has no inhibition to the tested virus.