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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Exp Eye Res. 2016 Oct 11;153:90–100. doi: 10.1016/j.exer.2016.10.010

Figure 6. Kynurenine pathway in corneal stromal tissue isolated from healthy controls (HC), Type 1 (T1DM) and Type 2 (T2DM) diabetes mellitus patients.

Figure 6

Significant upregulation of tryptophan metabolism is measured in T1DM corneal tissue with increased xanthurenic acid and kynurenic acid. Nicotinate levels were significantly increased in T2DM corneal samples. n≥4 for HC, T1DM, and T2DM corneal buttons. Error bars represent standard error of the mean. A one-way ANOVA was performed and P≤0.05 considered statistically significant. Each data point corresponds to an individual patient.