Table 1.
Outcome of adolescents and young adults with type 2 diabetes after bariatric surgery
| Author | n (b) | n (f) | Age (years) | Operation | BMI (b) | Follow-up | Outcome | Comments |
|---|---|---|---|---|---|---|---|---|
| Messiah et al. (38) | 65 | 18.5 (11–19)* | AGB | 46 kg/m2* | 1 year | 59% improvement | Diabetes outcomes reported as part of larger AGB series (n = 436). Data from 65% of all AGB patients in the larger series were missing at 1 year. Specific loss to follow-up and definitions for change in diabetes status (or improvement) was not provided. | |
| Messiah et al. (38) | 67 | 18.5 (11–19)* | RYGB | 51 kg/m2* | 1 year | 79% improvement | Diabetes outcomes reported as part of larger RYGB series (n = 454). Data from 76% of all RYGB patients in the larger series were missing at 1 year. Specific loss to follow-up and definitions for change in diabetes status (or improvement) was not provided. | |
| Inge et al. (43) | 11 | 9 | 17.8 (14–21) | RYGB | 50 kg/m2 | 1 year | 88% remission | Analysis contains only those with diabetes. BMI decreased by 33% over 1 year. Remission defined as HbA1c <6.5% (or FBG <126 mg/dL) and off of diabetes medications. Nine of 11 patients had sufficient biochemical and medication use data at 1 year to score remission. |
| Inge et al. (2) | 23 | 18 | 17 (13–19)* | RYGB | 54 kg/m2* | 3 years | 94% remission† | Diabetes outcomes reported as part of larger series. Remission defined as HbA1c <6.5% (or FBG <126 mg/dL) and off of medications. |
| Inge et al. (2) | 6 | 2 | 17 (13–19)* | VSG | 50 kg/m2* | 3 years | 68% remission | Diabetes outcomes reported as part of larger series. Remission defined as HbA1c <6.5% (or FBG <126 mg/dL) and off of medications. |
| Alqahtani et al. (39) | 52 | 52 | 14.4 (4.9–21)* | VSG | 48 kg/m2* | 3 years | 89% remission | Diabetes outcomes reported as part of larger series. Remission defined as HbA1c <6.5% (or FBG <126 mg/dL) and off of medications. |
| Alqahtani et al. (37) | 11 | 11 | 11.2 | VSG | 45 kg/m2 | 5 years | 100% remission | Diabetes outcomes reported as part of larger series. Remission defined as HbA1c <6.5% (or FBG <126 mg/dL) and off of medications. |
AGB, adjustable gastric band; BMI (b), BMI at baseline; FBG, fasting blood glucose; n (b), number in sample at baseline; n (f), number in sample at final time point; RYGB, Roux-en-Y gastric bypass; VSG, vertical sleeve gastrectomy.
*
Data derived from the larger series in the analysis and is not specific to the diabetes subpopulation.
†
Remission data were modeled, taking into account the influence of missing data.