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. 2017 Feb 14;12:1251–1264. doi: 10.2147/IJN.S125866

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© 2017 Gao et al. This work is published and licensed by Dove Medical Press Limited

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CQ enhances antigen cross-presentation by BMDCs.

Notes: (A) The percentage of OT-I CD8⁺ T-cells that proliferated after coculture with BMDCs pulsed with OVA and 30 μM CQ. (B) Representative flow cytometric histograms and (C) scatter plots from (A) are shown. The data were analyzed by one-way ANOVA, followed by a multiple comparison post-test. ***P<0.001. Data represent the mean ± SD from three repeated experiments with n =2–4.

Abbreviations: ANOVA, analysis of variance; BMDCs, bone marrow-derived dendritic cells; CFSE, carboxyfluorescein diacetate N-succinimidyl ester; CQ, chloroquine; OVA, ovalbumin; PBS, phosphate-buffered saline.