Table 2. Unadjusted and Adjusted Rates of Short-Term or Intermediate-Term Events in Subjects Included in the Analysis.

Outcomes	Subjects who underwent non-therapeutic angiograms (n = 89)	Subjects who received IV rt-PA alone (n = 222)	Unadjusted OR (95% CI);p-value	Adjusted OR (95% CI);p-value
Neurological deterioration within 24 (±6) h*	9/83 (10.8)	29/209 (13.9)	0.7 (0.3–1.7); p = 0.49	1 (0.4–2.3); p = 1
Symptomatic ICH within 30 h	2 (2.2)	13 (5.9)	0.4 (0.1–1.7); p = 0.2	0.4 (0.1–1.8); p = 0.2
AKI within 5 (±1) days or hospital discharge	1 (1.1)	3 (1.3)	0.8 (0.1–8.1); p = 0.87	0.8 (0.1–8.3); p = 0.89
Major non-ICH within 5 (±1) days or hospital discharge	1 (1.1)	5 (2.3)	0.5 (0.1–4.3); p = 0.52	0.5 (0.1–4.8); p = 0.55
Any deaths within 90 days	6 (6.7)	48 (21.6)	0.3 (0.1–0.6); p = 0.003**	0.3 (0.1–0.8); p = 0.015**
Recurrent stroke within 90 days	2 (2.2)	14 (6.3)	0.3 (0.1–1.5); p = 0.16	0.5 (0.1–2.4); p = 0.38
Functional independence at 90 (±14) days	56 (62.9)	90 (40.5)	2.5 (1.5–4.1); p < 0.001**	2 (1.1–3.5); p = 0.016**

Abbreviations: OR: odds ratio; CI: confidence interval; IV: intravenous; rt-PA: recombinant tissue plasminogen activator; AKI: acute kidney injury

^*NIHSS score at 24 (±6) h was available for 83/89 patients who underwent catheter-based non-therapeutic angiograms and for 209/222 patients who did not undergo catheter-based angiogram.

^**Significant p-values at <0.05 level of significance.