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. 2017 Feb 15;10:885–894. doi: 10.2147/OTT.S122992

Figure 4.

Figure 4

Upregulation of miR-320a inhibited c-Myc expression and hepatocellular carcinoma cells proliferation by targeting c-Myc in vitro.

Notes: After HepG2 and QGY-7703 cell lines treated with miR-320a mimics or c-Myc siRNA. Western blot assays of c-Myc protein were conducted in HepG2 (A) and QGY-7703 (B) cells and β-Actin was used as a control. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assays were conducted in HepG2 cell line (C) and QGY-7703 cell line (D). Data are presented as the mean ± standard deviation (n=3). Results were obtained in three replicates. **P<0.01.

Abbreviations: miR-320a, microRNA-320a; NC, negative control; OD, optical density; si or siRNA, small interfering RNA.