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. 2017 Feb 15;10:879–884. doi: 10.2147/OTT.S128391

Table 2.

Univariate Cox regression analysis for OS and DFS in patients with laryngeal squamous cell carcinoma

Variables No of patients OS
DFS
No of events HR (95% CI) P-value No of events HR (95% CI) P-value
Sex 0.11 0.08
 Male 119 39 43
 Female 10 1 0.20 (0.03–1.47) 1 0.18 (0.02–1.28)
Age, years 0.26 0.97
 ≤60 64 23 22
 >60 65 17 0.70 (0.37–1.31) 22 0.97 (0.54–1.75)
Smoking 0.78 0.67
 Nonsmoker or ex-smoker 51 19 20
 Smoker 78 21 1.23 (0.67–1.99) 24 1.06 (0.56–1.76)
Nodal classification <0.01 <0.01
 N0 87 14 22
 N+ 42 26 4.58 (2.42–8.61) 20 2.43 (1.33–4.45)
Disease stage ,0.01 <0.01
 I/II 80 12 19 4.68 (2.49–8.81)
 III/IV 49 28 5.94 (2.99–11.78) 25
CRP/ALB ratio <0.05 <0.01
 <0.047 73 17 18
 ≥0.047 56 23 2.13 (1.15–3.93) 26 2.36 (1.28–4.36)

Abbreviations: CRP/ALB, C-reactive protein/albumin; CI, confidence interval; DFS, disease-free survival; HR, hazard ratio; OS, overall survival.