Table 2.
Variables | No of patients | OS
|
DFS
|
||||
---|---|---|---|---|---|---|---|
No of events | HR (95% CI) | P-value | No of events | HR (95% CI) | P-value | ||
Sex | 0.11 | 0.08 | |||||
Male | 119 | 39 | 43 | ||||
Female | 10 | 1 | 0.20 (0.03–1.47) | 1 | 0.18 (0.02–1.28) | ||
Age, years | 0.26 | 0.97 | |||||
≤60 | 64 | 23 | 22 | ||||
>60 | 65 | 17 | 0.70 (0.37–1.31) | 22 | 0.97 (0.54–1.75) | ||
Smoking | 0.78 | 0.67 | |||||
Nonsmoker or ex-smoker | 51 | 19 | 20 | ||||
Smoker | 78 | 21 | 1.23 (0.67–1.99) | 24 | 1.06 (0.56–1.76) | ||
Nodal classification | <0.01 | <0.01 | |||||
N0 | 87 | 14 | 22 | ||||
N+ | 42 | 26 | 4.58 (2.42–8.61) | 20 | 2.43 (1.33–4.45) | ||
Disease stage | ,0.01 | <0.01 | |||||
I/II | 80 | 12 | 19 | 4.68 (2.49–8.81) | |||
III/IV | 49 | 28 | 5.94 (2.99–11.78) | 25 | |||
CRP/ALB ratio | <0.05 | <0.01 | |||||
<0.047 | 73 | 17 | 18 | ||||
≥0.047 | 56 | 23 | 2.13 (1.15–3.93) | 26 | 2.36 (1.28–4.36) |
Abbreviations: CRP/ALB, C-reactive protein/albumin; CI, confidence interval; DFS, disease-free survival; HR, hazard ratio; OS, overall survival.