Table 2.

Relationship of VEGF –460T/C genotype and allele with the clinical characteristics of the patients

Characteristics	Genotype			T-allele	C-allele	OR	95% CI	P-value
	T/T	T/C	C/C
Gender								0.835
Male	122	87	23	331	133
Female	56	41	9	153	59	0.946	0.561–1.595
Age, years								0.259
≤45	83	75	16	241	107
>45	95	54	15	244	84	0.756	0.465–1.229
Clinical classification								0.916
II	21	15	4	57	23
III–IV	158	114	26	430	166	0.960	0.455–2.207
T classification								0.446
T1–2	35	21	4	91	29
T3–4	143	108	27	394	162	1.290	0.669–2.488
N classification								0.015*
N0–1	112	64	5	288	74
N2–3	66	64	27	196	118	1.820	1.118–2.962
M classification								0.077
M0	166	104	27	436	158
M1	12	25	4	49	33	1.842	0.929–3.654
Local recurrence								0.741
Yes	12	6	2	30	10
No	166	122	30	454	182	1.192	0.420–3.379
Disease progression								0.158
Yes	23	37	4	83	45
No	156	91	27	403	145	0.656	0.365–1.181

Note:

^*P<0.05 was considered statistically significant.

Abbreviations: CI, confidence interval; OR, odds ratio; VEGF, vascular endothelial growth factor.