Table 2.

ACCORD LIPID and EYE TRIAL outcomes⁵⁸,⁶⁰

Endpoint		Simvastatin + fenofibrate (N)	Simvastatin + placebo (N)	Hazard ratio (p-value)
Primary outcomes	Major CV event (nonfatal MI, nonfatal stroke or death from CV cause)	291	310	0.92 (0.32)
Secondary outcomes	Primary outcome plus revascularization or hospitalization for CHD	641	667	0.94 (0.3)
	Major CHD event	332	353	0.92 (0.26)
	Nonfatal MI	173	186	0.91 (0.39)
	Stroke	98	88	1.05 (0.8)
	All-cause mortality	302	335	0.91 (0.33)
	Fatal or nonfatal CHD	120	143	0.82 (0.1)
Other	Progression of diabetic retinopathy	52	80	0.6 (0.006)
	Moderate vision loss	227	233	0.95 (0.57)

Abbreviations: CV, cardiovascular; MI, myocardial infarction; CHD, coronary heart disease