Table 2.
Effect of FE + RTP, VE + RTP, and RTP Only on Outcomes at Each Evaluation Time Point
| Outcome Measure | FE + RTP (n = 6) | VE + RTP (n = 6) | RTP Only (n = 5) | ||||||
| Baseline | EOT | EOT + 4a | Baseline | EOT | EOT + 4 | Baseline | EOT | EOT + 4 | |
| FMA score, M (SD) | 36.2 (7.4) | 48.5b (6.8) | 52.5 (0.6) | 30.5 (12.9) | 35.3 (14.6) | 37.0 (17.6) | 25.4 (7.8) | 29.8 (12.0) | 33.4 (15.0) |
| WMFT | |||||||||
| Total performance time, s, M (SD) | 3.8 (6.0) | 4.4 (10.74) | 3.9 (7.0) | 11.6 (25.0) | 11.6 (22.4) | 14.8 (28.8) | 13.0 (23.2) | 14.2 (27.3) | 10.5 (20.2) |
| Gross motor performance time—tasks, s (Timed Tasks 1–7), M (SD) | 1.8 (3.3) | 0.8 (0.5) | 0.7 (0.4) | 5.5 (12.1) | 6.8 (15.2) | 6.3 (21.4) | 2.7 (6.1) | 2.4 (4.7) | 2.3 (4.6) |
| Performance time—fine motor tasks, s (Timed Tasks 8–15), M (SD) | 5.7 (7.2) | 7.4 (14.0) | 6.7 (8.6) | 20.3 (34.2) | 18.8 (28.4) | 25.0 (33.6) | 23.5 (29.0) | 25.9 (34.5) | 18.6 (25.8) |
| Weight to box, lb, M (SD) | 17.3 (2.0) | 18.7 (1.3) | 20.0 (0.0) | 8.7 (3.2) | 12.3 (2.4) | 14.3 (2.0) | 8.0 (3.5) | 8.4 (4.0) | 9.2 (4.1) |
| Grip, kg, M (SD) | 21.5 (2.9) | 23.8 (3.5) | 28.1 (3.3) | 10.3 (3.0) | 12.0 (2.9) | 11.7 (3.1) | 9.0 (1.9) | 11.3 (1.8) | 12.3 (1.6) |
| No. of tasks not completed within 120 s, total, M (SD) | 0.3 (0.8) | 0.0 (0.0) | 0.0 (0.0) | 3.8 (4.6) | 3.3 (4.4) | 2.7 (3.3) | 3.4 (4.7) | 2.8 (3.8) | 3.2 (4.4) |
| No. of gross motor tasks not completed within 120 s, (SD) | 0.0 (0.0) | 0.0 (0.0) | 0.0 (0.0) | 0.7 (1.2) | 0.5 (1.2) | 0.5 (0.8) | 1.2 (1.8) | 1.0 (1.4) | 1.2 (1.8) |
| No. of fine motor tasks not completed within 120 s, M (SD) | 0.3 (0.8) | 0.0 (0.0) | 0.0 (0.0) | 3.2 (3.6) | 2.8 (3.4) | 2.2 (2.6) | 2.2 (3.0) | 1.8 (2.5) | 2.0 (2.7) |
| Functional Ability Score | 4.0 (0.6) | 4.6 (0.4) | 4.8 (0.2) | 2.9 (1.3) | 3.3 (1.2) | 3.4 (1.3) | 2.8 (1.0) | 3.3 (1.3) | 3.4 (1.4) |
| Peak VO2 | 21.9 (7.5) | 23.2 (5.1) | N/A | 16.3 (3.5) | 18.7 (4.1)b | NA | 16.0 (3.3) | 15.5 (3.6) | NA |
Note. EOT = end of treatment; EOT + 4 = end of treatment + 4 wk; FE = forced exercise; FMA = Fugl–Meyer Assessment; M = mean; NA = not applicable; RTP = repetitive task practice; SD = standard deviation; VE = voluntary exercise; VO2 = volume of oxygen uptake; WMFT = Wolf Motor Function Test.
a
n = 5, secondary to 1 participant receiving botulinum toxin before EOT + 4.
b
Significant change from baseline, p < .05.