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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Curr Opin Genet Dev. 2016 Sep 16;41:77–84. doi: 10.1016/j.gde.2016.08.005

Figure 2.

Figure 2

Figure 2

Figure 2

Geographic distribution of Trypansoma brucei and APOL1 risk variants. (A) Cumulative incidence from 1990 to 2014 of human African trypanosomiasis due to Trypansoma brucei gambiense (gHAT) and Trypanosoma brucei rhodesiense (rHAT) [75]. Uganda is the only country reporting trypanosomiasis due to both subspecies, with a higher cumulative incidence of gHAT. (B) Global frequency distribution of the G allele of the S342G mutation [11,12,28,49,76–78]. The Esan in Nigeria have the highest frequency (49.5%). (C) Global frequency distribution of the G2 deletion [12,28,32,49,77]. Bantu-speaking people in South Africa (Herero, Ovambo, Pedi, Sotho, Tswana, and Zulu) have the highest frequency (21.4%).