. Author manuscript; available in PMC: 2018 Mar 1.

Published in final edited form as: Arch Biochem Biophys. 2016 Nov 10;617:145–154. doi: 10.1016/j.abb.2016.11.003

Table 1.

Usage of HNE concentration in signaling study

HNE concentration (μM)	Percentage of studies (%)
≥500	1.7
100<HNE<500	1.7
50<HNE≤100	11.7
10<HNE≤50	38.0
1<HNE≤10	29.0
0.1≤HNE≤1	16.8
<0.1	1.1

Note. HNE concentration was calculated from the amount of HNE added and volume of medium or buffer and was based on 179 studies of HNE effect on signaling molecules/pathways from 1987-2015.