Table 1.

Superficial and deep layer cartilage transverse relaxation time (T2) and cartilage thickness in various compartments, plates, and subregions of the femorotibial joint

	Superficial Layer			Deep Layer			Cartilage Thickness
	Mean ± SD	[95% CI]	P-Value	Mean ± SD	[95% CI]	P-Value	Mean ± SD	[95% CI]
Composite measures:
FTJ	45.4 ± 2.3	[44.9, 45.9]		35.8 ± 1.8	[35.4, 36.2]		7.4 ± 0.9	[7.2, 7.5]
MFTC	45.6 ± 2.8	[45.0, 46.1]		36.3 ± 2.2	[35.8, 36.7]		3.5 ± 0.5	[3.4, 3.6]
LFTC	45.3 ± 2.4	[44.8, 45.8]		35.4 ± 2.0	[35.0, 35.8]		3.8 ± 0.5	[3.7, 3.9]
cMFTC	46.2 ± 3.3	[45.5, 46.9]		32.1 ± 2.6	[31.6, 32.6]		4.6 ± 0.7	[4.5, 4.7]
cLFTC	44.0 ± 3.1	[43.3, 44.6]		31.2 ± 2.1	[30.7, 31.6]		5.3 ± 0.8	[5.2, 5.5]
Medial tibia (MT):
MT	41.5 ± 2.9	[40.9, 42.1]		33.0 ± 1.9	[32.6, 33.4]		1.7 ± 0.2	[1.7, 1.7]
cMT	42.2 ± 4.1	[41.4, 43.1]	0.027	29.0 ± 2.1	[28.5, 29.4]	<0.001	2.4 ± 0.4	[2.3, 2.4]
eMT	44.0 ± 4.2	[43.1, 44.9]	<0.001	34.9 ± 3.1	[34.3, 35.5]	<0.001	1.5 ± 0.2	[1.4, 1.5]
iMT	37.0 ± 3.8	[36.2, 37.8]	<0.001	32.2 ± 3.9	[31.4, 33.0]	0.001	1.8 ± 0.2	[1.8, 1.9]
aMT	41.5 ± 3.8	[40.8, 42.3]	0.953	33.1 ± 2.4	[32.6, 33.6]	0.469	1.5 ± 0.2	[1.5, 1.5]
pMT	41.9 ± 3.6	[41.2, 42.7]	0.066	36.3 ± 2.5	[35.7, 36.8]	<0.001	1.4 ± 0.2	[1.4, 1.5]
Central medial femur (cMF):
cMF	49.6 ± 3.7	[48.8, 50.4]		39.5 ± 3.5	[38.8, 40.2]		1.8 ± 0.3	[1.8, 1.9]
ccMF	50.2 ± 4.2	[49.3, 51.0]	0.007	35.2 ± 4.0	[34.4, 36.1]	<0.001	2.2 ± 0.4	[2.2, 2.3]
ecMF	44.6 ± 4.2	[43.7, 45.4]	<0.001	38.0 ± 4.0	[37.2, 38.8]	<0.001	1.3 ± 0.2	[1.3, 1.3]
icMF	52.8 ± 4.9	[51.8, 53.8]	<0.001	44.9 ± 5.7	[43.7, 46.1]	<0.001	1.9 ± 0.3	[1.9, 2.0]
Lateral tibia (LT):
LT	42.4 ± 2.5	[41.9, 42.9]		31.0 ± 1.9	[30.6, 31.4]		2.1 ± 0.3	[2. 0, 2.2]
cLT	38.5 ± 3.8	[37.7, 39.3]	<0.001	26.7 ± 2.6	[26.2, 27.2]	<0.001	3.3 ± 0.6	[3.1, 3.4]
eLT	46.2 ± 3.9	[45.4, 47.0]	<0.001	34.9 ± 3.0	[34.3, 35.5]	<0.001	1.7 ± 0.2	[1.6, 1.7]
iLT	40.9 ± 4.5	[40.0, 41.9]	<0.001	32.0 ± 3.7	[31.2, 32.7]	0.002	2.0 ± 0.4	[2.0, 2.1]
aLT	42.5 ± 3.0	[41.8, 43.1]	0.738	30.5 ± 2.6	[29.9, 31.0]	0.020	1.7 ± 0.3	[1.6, 1.7]
pLT	45.4 ± 3.6	[44.6, 46.1]	<0.001	33.4 ± 3.3	[32.8, 34.1]	<0.001	1.9 ± 0.3	[1.9, 2.0]
Central lateral femur (cLF):
cLF	48.1 ± 2.9	[47.5, 48.7]		39.7 ± 2.8	[39.2, 40.3]		1.7 ± 0.2	[1.7, 1.8]
ccLF	49.4 ± 3.8	[48.7, 50.2]	<0.001	35.7 ± 3.2	[35.0, 36.3]	<0.001	2.1 ± 0.3	[2.0, 2.1]
ecLF	45.5 ± 3.6	[44.7, 46.2]	<0.001	40.8 ± 3.5	[40.1, 41.6]	0.002	1.5 ± 0.2	[1.4, 1.5]
icLF	48.6 ± 4.4	[47.7, 49.6]	0.241	44.2 ± 4.3	[43.3, 45.1]	<0.001	1.6 ± 0.2	[1.6, 1.7]

SD: standard deviation; 95% CI: 95% confidence intervals; P: Wilcoxon signed rank test for differences between subregional T2 and T2 in the respective cartilage. Cartilage thickness for the n=92 participants measurements were adapted from (Eckstein et al., 2010). FTJ: femorotibial joint; MFTC/LFTC: medial/lateral femorotibial compartment; cMFTC/cLFTC: central medial/lateral compartment; c/e/i/a/p M/LT: central/external/internal/anterior/posterior medial/lateral tibia; c/e/i cM/LF: central/external/internal medial/lateral femur.