Table 2.
Levels of TSNAs in mainstream smoke of domestic cigarettes tested with the ISO machine-smoking regimen. The cigarettes are rank-ordered highest to lowest total TSNA yield.
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| Tobacco-Specific Nitrosamines (ng/cigarette)a,c | |||||
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| Cigarette Products‡ | NAB ± SD | NNK ± SD | NAT ± SD | NNN ± SD | Total ± SE |
| Winston Red 100s, HP | 22 ± 1.3 | 122.4 ± 10.5 | 145.1 ± 10.9 | 171.1 ± 14.8 | 460.8 ± 6.1 |
| Marlboro Red 100s, HP | 16.4 ± 1.0 | 80.7 ± 7.1 | 125.7 ± 11.8 | 134.9 ± 14.0 | 357.6 ± 5.8 |
| RJR Winston Red, HP | 17.7 ± 2.4 | 89.3 ± 14.6 | 111.3 ± 7.9 | 127 ± 15.7 | 345.4 ± 6.4 |
| Marlboro Red, SP | 15.3 ± 1.5 | 84.4 ± 11.1 | 114.1 ± 11.8 | 129.6 ± 21.8 | 343.1 ± 6.8 |
| Marlboro Red 100s, SP | 17.2 ± 1.3 | 71.5 ± 5.2 | 121.9 ± 9.5 | 131 ± 9.1 | 341.5 ± 5.0 |
| Salem Green, HP | 14.8 ± 2.2 | 82.3 ± 14.5 | 120 ± 20.9 | 114.7 ± 23.0 | 331.9 ± 7.8 |
| Marlboro Green, HP | 13.4 ± 1.4 | 76.9 ± 10.7 | 124 ± 8.0 | 112.3 ± 12.8 | 326.6 ± 5.7 |
| Marlboro Red, HP | 15.3 ± 1.1 | 72.1 ± 10.6 | 117.1 ± 11.1 | 118.7 ± 10.1 | 323.2 ± 5.7 |
| B&H Green 100s, HP | 16.2 ± 1.1 | 72.3 ± 6.3 | 117.7 ± 7.4 | 109.6 ± 6.9 | 315.8 ± 4.7 |
| Newport Green 100s, HP | 14.7 ± 2.3 | 57.4 ± 8.2 | 103.2 ± 14.1 | 125 ± 12.1 | 300.3 ± 6.1 |
| Winston Gold, HP | 15.4 ± 1.0 | 74.7 ± 6.7 | 96 ± 6.8 | 106.5 ± 8.4 | 292.6 ± 4.8 |
| Newport Green, SP | 14.1 ± 1.5 | 55.3 ± 5.7 | 98.1 ± 11.6 | 120.5 ± 21.8 | 288 ± 6.4 |
| Basic Gold 100s, SP | 17.6 ± 11.1 | 70.9 ± 16.8 | 89.2 ± 15.8 | 104.8 ± 17.7 | 282.5 ± 7.8 |
| USA Gold 100s, SP | 13.1 ± 1.3 | 57.1 ± 6.9 | 96.3 ± 6.6 | 108.4 ± 11 | 274.9 ± 5.1 |
| Marlboro Red Label, HP | 13.3 ± 0.9 | 62.7 ± 9.6 | 96.2 ± 8.2 | 101 ± 9.6 | 273.2 ± 5.3 |
| Basic Green 100s, HP | 12.7 ± 1.8 | 68.4 ± 8.8 | 86.1 ± 11.4 | 99.1 ± 16.7 | 266.3 ± 6.2 |
| Newport Green, HP | 12.3 ± 1.5 | 50.6 ± 7.1 | 87.3 ± 10.3 | 111.2 ± 14.3 | 261.5 ± 5.8 |
| Basic Gold 100s, HP | 12.9 ± 1.5 | 64.5 ± 14.8 | 87.6 ± 12.7 | 93.6 ± 11.2 | 258.6 ± 6.3 |
| Marlboro Menthol Gold, HP | 11.6 ± 1.6 | 63 ± 11.6 | 89.1 ± 9.8 | 91.9 ± 10.5 | 255.5 ± 5.8 |
| Marlboro Gold 100s, HP | 11.9 ± 1.3 | 56.2 ± 8.5 | 89 ± 15.5 | 92.1 ± 15.2 | 249.2 ± 6.3 |
| Kool Green, SP | 12.2 ± 1.5 | 62.8 ± 11.2 | 90.4 ± 8.4 | 80 ± 7.3 | 245.4 ± 5.3 |
| Kool Green, HP | 11.8 ± 1.7 | 61.2 ± 9.9 | 90.5 ± 12.1 | 78.6 ± 13.1 | 242.1 ± 6.1 |
| Marlboro Gold, SP | 11.8 ± 1.1 | 56.2 ± 5.0 | 86.2 ± 7.7 | 87.4 ± 9.6 | 241.7 ± 4.8 |
| Marlboro Gold, HP | 11.4 ± 1.0 | 54 ± 5.5 | 88.8 ± 7.1 | 86.6 ± 10.2 | 240.9 ± 4.9 |
| Marlboro Gold 100s, SP | 12.2 ± 0.8 | 52.2 ± 4.4 | 86.1 ± 3.9 | 85.3 ± 5.8 | 236.2 ± 3.9 |
| B&H Luxury 100s, SP | 11.8 ± 1.4 | 49.8 ± 6.5 | 83.3 ± 6.4 | 86.8 ± 7.5 | 231.8 ± 4.7 |
| Salem Gold, HP | 11.7 ± 2.1 | 56.6 ± 13.3 | 81.4 ± 14.5 | 79.7 ± 13.1 | 229.5 ± 6.6 |
| Merit Gold, SP | 10.5 ± 0.7 | 54.2 ± 15.4 | 77.5 ± 3.6 | 79.4 ± 6.7 | 221.7 ± 5.1 |
| Doral Gold, HP | 9.9 ± 0.9 | 68.5 ± 6.1 | 61 ± 6.0 | 69.6 ± 8.4 | 208.9 ± 4.6 |
| Camel Filters, HP | 10.6 ± 1.2 | 42.9 ± 3.6 | 79.3 ± 7.1 | 73.1 ± 2.1 | 206 ± 3.7 |
| Vantage Multicolor, SP | 9.5 ± 1.1 | 60.9 ± 8.9 | 64.2 ± 6.7 | 71.1 ± 14.0 | 205.6 ± 5.5 |
| Parliament Blue, HP | 10.5 ± 0.7 | 45.8 ± 8.3 | 72.1 ± 4.0 | 72.1 ± 3.2 | 200.6 ± 4.0 |
| Pall Mall Blue, HP | 9.1 ± 1.0 | 49.8 ± 5.4 | 59.6 ± 6.8 | 71.6 ± 6.4 | 190.1 ± 4.4 |
| VA Slim Gold Slims, HP | 9.5 ± 1.4 | 43.5 ± 4.7 | 67.3 ± 7.6 | 67.7 ± 5.7 | 189 ± 4.4 |
| Winston White 100s, HP | 10.9 ± 0.9 | 51.1 ± 3.2 | 58.3 ± 4.6 | 66.7 ± 5.9 | 187 ± 3.8 |
| Salem Gold 100s, HP | 9.2 ± 1.5 | 43.3 ± 5.5 | 64.9 ± 5.4 | 69.2 ± 8.7 | 186.6 ± 4.6 |
| Basic Blue 100s, HP | 9.9 ± 0.7 | 44.5 ± 3.4 | 57.4 ± 8.9 | 66.4 ± 9.9 | 178.2 ± 4.8 |
| Kent Golden, SP | 10.6 ± 1.0 | 35.9 ± 4.5 | 63.7 ± 6.8 | 66.7 ± 11 | 176.9 ± 4.8 |
| Camel Blue, HP | 9.4 ± 1.5 | 40.2 ± 9.8 | 65.2 ± 10.0 | 60.8 ± 11.3 | 175.5 ± 5.7 |
| Marlboro Silver 100s, HP | 8.8 ± 1.0 | 37.7 ± 2.8 | 62.7 ± 5.4 | 64.9 ± 5.0 | 174.1 ± 3.7 |
| Maverick Gold 100s, HP | 9.7 ± 1.2 | 43.8 ± 7.7 | 55.6 ± 4.3 | 64.5 ± 13.9 | 173.8 ± 5.2 |
| Marlboro Silver, HP | 9 ± 0.6 | 37.1 ± 5.4 | 61.7 ± 5.9 | 59.3 ± 6.0 | 167 ± 4.2 |
| Misty Blue Sims, HP | 8 ± 0.7 | 41.3 ± 3.3 | 51.5 ± 3.7 | 57.2 ± 6.2 | 158 ± 3.7 |
| Capri Magenta SS, HP | 8.8 ± 1.1 | 33.2 ± 6.2 | 60 ± 4.9 | 56 ± 8.6 | 158 ± 4.6 |
| Salem Silver 100s, HP | 7.8 ± 1.7 | 34.2 ± 7.2 | 49.3 ± 11.6 | 51.6 ± 12.6 | 142.9 ± 5.8 |
| Doral Silver 100s, HP | 6.9 ± 0.6 | 40.2 ± 3.6 | 41.8 ± 5.4 | 46.3 ± 5.7 | 135.3 ± 3.9 |
| True Silver, SP | 7.8 ± 1.0 | 19.3 ± 2.7 | 44.1 ± 3.9 | 51.8 ± 5.4 | 122.4 ± 3.6 |
| NOW Gold 100s, SP | 6.6 ± 0.6 | 23.2 ± 4.1 | 33.3 ± 3.8 | 31.8 ± 5.1 | 94.9 ± 3.7 |
| American Spirit Blue, HPb | 4.2 ± 0.9 | 21.4 ± 6.5 | 23.8 ± 3.8 | 17.2 ± 2.5 | 66.5 ± 3.7 |
| Carlton White 100s, HP | 4.5 ± 0.2 | 13 ± 1.7 | 18.6 ± 2.4 | 18.6 ± 3.6 | 54.8 ± 2.8 |
| 2R4F | 12.9 ± 1.1 | 115.6 ± 8.7 | 119 ± 8.5 | 133.1 ± 12.5 | 380.6 ± 17.5 |
NAB, N-nitrosoanabasine; NNK, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; NAT, N-nitrosoanatabine; and NNN, N-nitrosonornicotine; Total, (Sum of NNK, NAB, NAT, and NNN) (ng/cigarette); B&H, Benson and Hedges; HP, Hard Pack; SP, Soft Pack; SD, Standard deviation;
a
N= 7-replicate measurements; SE, Standard error;
b
100% Flue-cured tobacco;
c
American blend cigarette products