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. Author manuscript; available in PMC: 2017 Feb 21.
Published in final edited form as: Semin Cell Dev Biol. 2016 Sep 13;62:170–177. doi: 10.1016/j.semcdb.2016.09.005

Table 1.

hinge Variable target proteases
position human 15 14 13 12 11 10 9 8 7 6 5 4 3 2 1 1′ 2′ 3′ 4′
SerpinB3 G A E A A A A T A V V G F G S S P T S Papain, Cathepsin L, S, K
SerpinB4 * V * * * * * * * * * V V E L * S P * Chymase, Cathepsin G, Der P, Granzyme M
Mouse
serpinb3a G T E A A A A T G V E V S L T S A Q I Cathepsin K, L, S, V, G, papain, Der P, HMC
serpinb3b * * * * * * * * * * * * * V R * * * * Cathepsin L, G