Table 2.
Overall mortality by patient characteristics, sepsis origins, presence of bacteraemia and organ dysfunction by year of admission in Catalonia (2008–2012)
| Condition | N | Presence of condition (%) | In-hospital mortality (%) | |||||
|---|---|---|---|---|---|---|---|---|
| 2008 | 2009 | 2010 | 2011 | 2012 | p | |||
| Mortality | 23.7 | 23.6 | 22.0 | 20.4 | 19.7 | <.0001 | ||
| Source of sepsis | ||||||||
| Urinary tract | 30,600 | 33.6 | 35.0 | 37.1 | 39.8 | 38.8 | <.0001 | 13.9 |
| Respiratory tract | 26,748 | 34.2 | 34.0 | 31.2 | 30.9 | 32.7 | <.0001 | 24.2 |
| Abdomen | 9065 | 10.7 | 11.2 | 11.3 | 11.0 | 10.9 | NS | 28.0 |
| Skin and soft tissues | 3394 | 3.9 | 4.0 | 4.0 | 4.4 | 4.2 | NS | 20.3 |
| Endocarditis | 1326 | 1.8 | 1.8 | 1.9 | 1.4 | 1.4 | <.0001 | 27.3 |
| Device-related | 869 | 1.1 | 1.1 | 1.2 | 1.1 | 0.9 | .016 | 11.6 |
| CNS | 775 | 1.2 | 1.1 | 1.1 | 0.7 | 0.7 | <.0001 | 27.5 |
| Other | 31,149 | 37.4 | 37.5 | 39.2 | 38.1 | 37.1 | .001 | 15.1 |
| Bacteraemia | 20,285 | 25.5 | 25.5 | 24.5 | 24.8 | 23.5 | <.0001 | 39.3 |
| Organ dysfunction | ||||||||
| Kidney | 48,072 | 50.8 | 53.5 | 57.1 | 61.9 | 64.7 | <.0001 | 23.6 |
| Respiratory | 16,876 | 26.1 | 24.1 | 20.9 | 17.9 | 16.3 | <.0001 | 40.0 |
| CNS | 16,177 | 20.5 | 19.6 | 19.1 | 18.9 | 20.3 | <.0001 | 13.9 |
| Haematologic | 9158 | 11.6 | 12.3 | 12.2 | 11.2 | 9.1 | <.0001 | 22.4 |
| Cardiovascular | 3988 | 5.3 | 5.4 | 4.7 | 4.6 | 4.4 | <.0001 | 16.1 |
| Liver | 1058 | 1.0 | 1.3 | 1.3 | 1.3 | 1.4 | .029 | 55.9 |
| Number of organ failures | ||||||||
| 1 | 70,874 | 86.6 | 85.9 | 86.5 | 86.0 | 85.8 | NS | 18.5 |
| 2 | 9964 | 11.7 | 12.2 | 11.8 | 12.4 | 12.3 | 39.0 | |
| 3 or more | 1462 | 1.7 | 1.9 | 1.9 | 1.7 | 1.8 | 63.4 | |
Data are presented as number of cases or %
CNS central nervous system, NS non-significant