Table 1.
Sex and age groups of study cases in the primary and control datasets, by drug
| Primary dataset | Control dataset | ||||
|---|---|---|---|---|---|
| Mefloquine | Atovaquine-proguanil | Doxycycline | Chloroquine | Loperamide | |
| n (%) | n (%) | n (%) | n (%) | n (%) | |
| All cases | 933 (100) | 450 (100) | 3949 (100) | 422 (100) | 6724 (100) |
| Sex | |||||
| Male | 489 (52.4) | 198 (44.0) | 1506 (38.1) | 109 (25.8) | 3306 (49.2) |
| Female | 418 (44.8) | 224 (49.8) | 2308 (58.5) | 300 (71.1) | 3194 (47.5) |
| Unknown | 26 (2.8) | 28 (6.2) | 135 (3.4) | 13 (3.1) | 224 (3.3) |
| Age group, years | |||||
| <18 | 51 (5.5) | 35 (7.8) | 192 (4.9) | 22 (5.2) | 181 (2.7) |
| 18–65 | 595 (63.8) | 225 (50) | 1917 (48.5) | 216 (51.2) | 2659 (39.5) |
| 65+ | 287 (30.8) | 190 (42.2) | 1840 (46.6) | 184 (43.6) | 3884 (57.8) |
Across all strata, proportions varied significantly by drug, in both the primary dataset and in the pooled data overall (p < 0.05 by χ2 test)